Melatonin in Brain: From Circadian Signal to Neuroprotection
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چکیده
Due to the new findings on melatonin actions in the body, and the availability of melatonin analogs, the interest in the clinical applications of the neurohormone is increasing. The recent authorization of melatonin as a drug for insomnia treatment by the European Medicines Agency does it necessary to improve our knowledge regarding the melatonin synthesis, regulation, and actions in the brain. In this issue, the authors of the six contributions analyze the recent findings regarding melatonin-brain interactions, from chronobiological aspects to neurogenesis regulation. Here, a brief summary of the state of the art regarding the functions of melatonin, its brain receptors, and the neuroprotective properties of the indoleamine are shown.
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